As winter temperatures change, children with “adenovirus†infection causing pneumonia can be found everywhere in northern China. Among them, infants and young children aged from 6 months to 2 years are the majority. This type of pneumonia is heavier than other causes of bronchopneumonia, and it is easy to develop into persistent pneumonia or chronic pneumonia. It is harmful to children and occurs every year. Children died of adenovirus pneumonia and many families fell into deep misery.
Adenovirus pneumonia is a common disease in children in winter and spring. When suffering from illness, it usually has persistent high fever, heavy cough, massive lung inflammation, and severe hypoxia. Children with apathy, pale gray hair, cold extremities, abdominal distension, and sometimes vomiting and diarrhea appear 3-4 days after onset. Severe disease can be complicated by toxic encephalopathy, and it may cause drowsiness, convulsions, and coma. It is a child disease with a high mortality rate. The main cause of adenovirus pneumonia is caused by adenovirus. Now adenovirus is known to have 41 serotypes. Adenovirus is a DNA virus. It mainly reproduces in the nucleus, and has strong ability to resist temperature, acid and grease. Pharyngeal, conjunctival and lymphoid tissues also reproduce in the intestine, and adenovirus pneumonia has a wide range of lesions. At present, how to effectively eliminate adenovirus has become a major problem in the world medical field!
Recently, Liu Lei experts from Harbin Medical University have made major breakthroughs in this field. Professor Liu isolated the purified human adenovirus strain by extracting throat swab specimens from children with respiratory infections in Harbin, and used cinnamaldehyde for the anti-virus experiment. The experiment mainly extracted adenoviral DNA. 18 pairs of primers were designed based on GENEBANK uploads of AY599834 (type 3) and AY594255 (type 7) sequences. Cinnamaldehyde, the main component of cinnamon oil, was selected for anti-adenovirus studies. The effect of cinnamaldehyde on ADV was observed by cytopathic inhibition assay (CPE) and thiazolyl blue (MTT) colorimetry. The results showed that cinnamaldehyde has anti-ADV effect, and the main mode of action is the direct inactivation of the virus, inhibition of virus adsorption and virus replication.
Professor Liu’s discovery of this experiment quickly attracted the attention of relevant pharmaceutical manufacturers. Currently, some pharmaceutical manufacturers have started to develop anti-adenovirus pneumonia drugs containing cinnamaldehyde. It is reported that cinnamaldehyde has a good bactericidal effect, and itself has no effect on the human body. Any harm. Once successfully developed, it will greatly benefit children with adenovirus pneumonia and resolve the worries of thousands of mothers.
Adenovirus pneumonia is a common disease in children in winter and spring. When suffering from illness, it usually has persistent high fever, heavy cough, massive lung inflammation, and severe hypoxia. Children with apathy, pale gray hair, cold extremities, abdominal distension, and sometimes vomiting and diarrhea appear 3-4 days after onset. Severe disease can be complicated by toxic encephalopathy, and it may cause drowsiness, convulsions, and coma. It is a child disease with a high mortality rate. The main cause of adenovirus pneumonia is caused by adenovirus. Now adenovirus is known to have 41 serotypes. Adenovirus is a DNA virus. It mainly reproduces in the nucleus, and has strong ability to resist temperature, acid and grease. Pharyngeal, conjunctival and lymphoid tissues also reproduce in the intestine, and adenovirus pneumonia has a wide range of lesions. At present, how to effectively eliminate adenovirus has become a major problem in the world medical field!
Recently, Liu Lei experts from Harbin Medical University have made major breakthroughs in this field. Professor Liu isolated the purified human adenovirus strain by extracting throat swab specimens from children with respiratory infections in Harbin, and used cinnamaldehyde for the anti-virus experiment. The experiment mainly extracted adenoviral DNA. 18 pairs of primers were designed based on GENEBANK uploads of AY599834 (type 3) and AY594255 (type 7) sequences. Cinnamaldehyde, the main component of cinnamon oil, was selected for anti-adenovirus studies. The effect of cinnamaldehyde on ADV was observed by cytopathic inhibition assay (CPE) and thiazolyl blue (MTT) colorimetry. The results showed that cinnamaldehyde has anti-ADV effect, and the main mode of action is the direct inactivation of the virus, inhibition of virus adsorption and virus replication.
Professor Liu’s discovery of this experiment quickly attracted the attention of relevant pharmaceutical manufacturers. Currently, some pharmaceutical manufacturers have started to develop anti-adenovirus pneumonia drugs containing cinnamaldehyde. It is reported that cinnamaldehyde has a good bactericidal effect, and itself has no effect on the human body. Any harm. Once successfully developed, it will greatly benefit children with adenovirus pneumonia and resolve the worries of thousands of mothers.
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